Progesterone Quality Improvement Project


Progesterone is an evidence-based therapy shown to reduce preterm birth in women with prior preterm birth and/or short cervix through identification and treatment of appropriate candidates with progesterone prophylaxis.

Led by the Ohio Perinatal Quality Collaborative (OPQC) and Cincinnati Children’s Hospital Medical Center (CCHMC), this project has engaged 25 outpatient clinics and 20 charter hospitals throughout Ohio to test strategies to reduce the number of preterm births. By administering progesterone in the ideal time frames to women diagnosed with qualifying conditions, the goal is to reduce the number of preterm births for women in two high-risk categories: before 32 weeks and before 37 weeks.

Through the Progesterone Project, OPQC also seeks to identify barriers to the administration of Progesterone, such as precertification or payment, so they can responsively act on the information to ensure all eligible women are receiving treatment early in pregnancy.

This project is funded by the Ohio Department of Medicaid and the Ohio Department of Health.